Evidence for co-evolution between human microRNAs and Alu-repeats.

This paper connects Alu repeats, the most abundant repetitive elements in the human genome and microRNAs, small RNAs that alter gene expression at the post-transcriptional level. Base-pair complementarity could be demonstrated between the seed sequence of a subset of human microRNAs and Alu repeats...

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Bibliographic Details
Main Authors: Stefan Lehnert, Peter Van Loo, Pushpike J Thilakarathne, Peter Marynen, Geert Verbeke, Frans C Schuit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2637760?pdf=render