Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions

Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions

Abstract Background Cimbi-36 can be 11C-labeled to form an agonist radioligand used for positron emission tomography (PET) imaging of the 5-HT2A receptor in the brain. In its non-labeled form (25B-NBOMe), it is used as a recreational drug that can lead to severe adverse effects, in some cases, with...

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Bibliographic Details
Main Authors: Annette Johansen, Søren Holm, Bente Dall, Sune Keller, Jesper L. Kristensen, Gitte M. Knudsen, Hanne D. Hansen
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:EJNMMI Research
Subjects:
11C-Cimbi-36
25B-NBOMe
5-HT2A receptor
Biodistribution
Pharmacology
Pharmacokinetics
Online Access:http://link.springer.com/article/10.1186/s13550-019-0527-4

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http://link.springer.com/article/10.1186/s13550-019-0527-4

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