The Clinical Significance of O6-Methylguanine-DNA Methyltransferase Promoter Methylation Status in Adult Patients With Glioblastoma: A Meta-analysis

Background and objectivePromoter status of O6-methylguanine-DNA methyltransferase (MGMT) has been widely established as a clinically relevant factor in glioblastoma (GBM) patients. However, in addition to varied therapy schedule, the prognosis of GBM patients is also affected by variations of age, r...

Full description

Bibliographic Details
Main Authors: Yu-Hang Zhao, Ze-Fen Wang, Chang-Jun Cao, Hong Weng, Cheng-Shi Xu, Kai Li, Jie-Li Li, Jing Lan, Xian-Tao Zeng, Zhi-Qiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2018.00127/full