IVIG regulates the survival of human but not mouse neutrophils

IVIG regulates the survival of human but not mouse neutrophils

Abstract Intravenous immunoglobulin (IVIG) are purified IgG preparations made from the pooled plasma from thousands of healthy donors and are being tested in preclinical mouse models. Inherent challenges, however, are the pluripotency of IVIG and its xenogeneicity in animals. IVIG can alter the viab...

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Bibliographic Details
Main Authors: Christoph Schneider, Simone Wicki, Stefanie Graeter, Tankica M. Timcheva, Christian W. Keller, Isaak Quast, Danila Leontyev, Iglika K. Djoumerska-Alexieva, Fabian Käsermann, Stephan M. Jakob, Petya A. Dimitrova, Donald R. Branch, Richard D. Cummings, Jan D. Lünemann, Thomas Kaufmann, Hans-Uwe Simon, Stephan von Gunten
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01404-0

Internet

https://doi.org/10.1038/s41598-017-01404-0

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