Membrane bound monomer of Staphylococcal alpha-hemolysin induces caspase activation and apoptotic cell death despite initiation of membrane repair pathway.
<h4>Background</h4>Wild type Staphylococcal alpha-hemolysin (alpha-HL) assembly on target mammalian cells usually results in necrotic form of cell death; however, caspase activation also occurs. The pathways of caspase activation due to binding/partial assembly by alpha-HL are unknown ti...
Main Authors: | Saumya S Srivastava, Satyabrata Pany, Amita Sneh, Neesar Ahmed, Aejazur Rahman, Krishnasastry V Musti |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-07-01
|
Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19621082/pdf/?tool=EBI |
Similar Items
-
Purification and properties of Staphylococcal Beta Hemolysin /
by: Haque, Riaz-ul
Published: (1963) -
Relationship between localization on cellular membranes and cytotoxicity of Vibrio vulnificus hemolysin.
by: Hiroyuki Sugiyama, et al.
Published: (2011-01-01) -
E. coli a-hemolysin: a membrane-active protein toxin
by: Goñi F.M., et al.
Published: (1998-01-01) -
Dysregulated hemolysin liberates bacterial outer membrane vesicles for cytosolic lipopolysaccharide sensing.
by: Shouwen Chen, et al.
Published: (2018-08-01) -
Membrane-Pore Forming Characteristics of the Bordetella pertussis CyaA-Hemolysin Domain
by: Chattip Kurehong, et al.
Published: (2015-04-01)