Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology

Human epidemiologic and genetic evidence using the Mendelian randomization approach in large-scale studies now strongly supports that elevated lipoprotein (a) [Lp(a)] is a causal risk factor for cardiovascular disease, that is, for myocardial infarction, atherosclerotic stenosis, and aortic valve st...

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Bibliographic Details
Main Authors: Børge G. Nordestgaard, Anne Langsted
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520345685