Metformin inhibits the function of granulocytic myeloid-derived suppressor cells in tumor-bearing mice

Metformin, an oral medicine broadly used for the treatment of type 2 diabetes, has been found to significantly improve tumor incidence and survival in large-scale clinical analysis. In recent years, the antitumor effect and mechanism of metformin have received much attention. Myeloid-derived suppres...

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Bibliographic Details
Main Authors: Peiqi Xu, Kai Yin, Xinyi Tang, Jie Tian, Yue Zhang, Jie Ma, Huaxi Xu, Qinglei Xu, Shengjun Wang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219336157