Interphase Microtubules Safeguard Mitotic Progression by Suppressing an Aurora B-Dependent Arrest Induced by DNA Replication Stress
Summary: The segregation of chromosomes is a critical step during cell division. This process is driven by the elongation of spindle microtubules and is tightly regulated by checkpoint mechanisms. It is unknown whether microtubules affect checkpoint responses as passive contributors or active regula...
Main Authors: | Guillaume Laflamme, Shannon Sim, Allen Leary, Mirela Pascariu, Jackie Vogel, Damien D’Amours |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-03-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221112471930230X |
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