Specific features of joint ultrasound study in patients with rheumatoid arthritis
Aim. To study the specific features of joint ultrasound readings in rheumatoid arthritis (RA) in relation to its duration. Subjects and methods. A total of 162 patients (mean age, 43.54±11.1 years) with a mean RA duration of 3.22±3.13 years were examined. Gray-scale ultrasound study (USS) of hand an...
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doaj-a569f71983484a519f5c511e3f21fa832020-11-25T03:14:09Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422017-01-01891535610.17116/terarkh2016881153-5629192Specific features of joint ultrasound study in patients with rheumatoid arthritisE B KomarovaO A RebrovaI I PokrushkaYu G KindritskayaAim. To study the specific features of joint ultrasound readings in rheumatoid arthritis (RA) in relation to its duration. Subjects and methods. A total of 162 patients (mean age, 43.54±11.1 years) with a mean RA duration of 3.22±3.13 years were examined. Gray-scale ultrasound study (USS) of hand and ankle joints was performed using color Doppler energy imaging. Group 1 included 78 patients with a RA duration of less than 2 years; Group 2 consisted of 84 patients with a RA duration of more than 2 years. Results. Joint USS diagnosed osteochondral erosions twice more frequently than conventional radiography. 82% of the patients with RA were found to have synovitis; 77% had thickening of the synovial membrane (SM) with hypervascularization, the vascularization intensity scores of 2—3 being predominant; and 54% had tenosynovitis of the carpal extensor tendon. Effusion into the joint cavity, SM hypervascularization scores of 2—3, and tenosynovitis were most common in Group 1. SM thickening and osteochondral erosions were prevalent in Group 2. Conclusion. Joint USS revealed that angiogenesis and inflammation were dominant in the patients with a RA duration of less than 2 years and the proliferative-destructive processes were prevalent in those with a RA duration of more than 2 years. Identifying the predominance of pathophysiological processes in each specific patient with RA will be able to individualize therapy and to improve the prognosis of the disease.https://ter-arkhiv.ru/0040-3660/article/viewFile/32192/pdfrheumatoid arthritisjoint ultrasound studydisease durationangiogenesisdestruction |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
E B Komarova O A Rebrova I I Pokrushka Yu G Kindritskaya |
spellingShingle |
E B Komarova O A Rebrova I I Pokrushka Yu G Kindritskaya Specific features of joint ultrasound study in patients with rheumatoid arthritis Терапевтический архив rheumatoid arthritis joint ultrasound study disease duration angiogenesis destruction |
author_facet |
E B Komarova O A Rebrova I I Pokrushka Yu G Kindritskaya |
author_sort |
E B Komarova |
title |
Specific features of joint ultrasound study in patients with rheumatoid arthritis |
title_short |
Specific features of joint ultrasound study in patients with rheumatoid arthritis |
title_full |
Specific features of joint ultrasound study in patients with rheumatoid arthritis |
title_fullStr |
Specific features of joint ultrasound study in patients with rheumatoid arthritis |
title_full_unstemmed |
Specific features of joint ultrasound study in patients with rheumatoid arthritis |
title_sort |
specific features of joint ultrasound study in patients with rheumatoid arthritis |
publisher |
"Consilium Medicum" Publishing house |
series |
Терапевтический архив |
issn |
0040-3660 2309-5342 |
publishDate |
2017-01-01 |
description |
Aim. To study the specific features of joint ultrasound readings in rheumatoid arthritis (RA) in relation to its duration. Subjects and methods. A total of 162 patients (mean age, 43.54±11.1 years) with a mean RA duration of 3.22±3.13 years were examined. Gray-scale ultrasound study (USS) of hand and ankle joints was performed using color Doppler energy imaging. Group 1 included 78 patients with a RA duration of less than 2 years; Group 2 consisted of 84 patients with a RA duration of more than 2 years. Results. Joint USS diagnosed osteochondral erosions twice more frequently than conventional radiography. 82% of the patients with RA were found to have synovitis; 77% had thickening of the synovial membrane (SM) with hypervascularization, the vascularization intensity scores of 2—3 being predominant; and 54% had tenosynovitis of the carpal extensor tendon. Effusion into the joint cavity, SM hypervascularization scores of 2—3, and tenosynovitis were most common in Group 1. SM thickening and osteochondral erosions were prevalent in Group 2. Conclusion. Joint USS revealed that angiogenesis and inflammation were dominant in the patients with a RA duration of less than 2 years and the proliferative-destructive processes were prevalent in those with a RA duration of more than 2 years. Identifying the predominance of pathophysiological processes in each specific patient with RA will be able to individualize therapy and to improve the prognosis of the disease. |
topic |
rheumatoid arthritis joint ultrasound study disease duration angiogenesis destruction |
url |
https://ter-arkhiv.ru/0040-3660/article/viewFile/32192/pdf |
work_keys_str_mv |
AT ebkomarova specificfeaturesofjointultrasoundstudyinpatientswithrheumatoidarthritis AT oarebrova specificfeaturesofjointultrasoundstudyinpatientswithrheumatoidarthritis AT iipokrushka specificfeaturesofjointultrasoundstudyinpatientswithrheumatoidarthritis AT yugkindritskaya specificfeaturesofjointultrasoundstudyinpatientswithrheumatoidarthritis |
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