Prostaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis.

Prostaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis.

Respiratory viruses cause substantial disease and are a significant healthcare burden. Virus-induced inflammation can be detrimental to the host, causing symptoms during acute infection and leading to damage that contributes to long-term residual lung disease. Prostaglandin E2 (PGE2) is a lipid medi...

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Bibliographic Details
Main Authors: Mary K McCarthy, Rachael E Levine, Megan C Procario, Peter J McDonnell, Lingqiao Zhu, Peter Mancuso, Leslie J Crofford, David M Aronoff, Jason B Weinberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3797793?pdf=render

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http://europepmc.org/articles/PMC3797793?pdf=render

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