Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study.
BACKGROUND:Trauma is the leading cause of death and disability in patients aged 1-46 y. Severely injured patients experience considerable blood loss and hemorrhagic shock requiring treatment with massive transfusion of red blood cells (RBCs). Preclinical and retrospective human studies in trauma pat...
Main Authors: | Brant M Wagener, Parker J Hu, Joo-Yeun Oh, Cilina A Evans, Jillian R Richter, Jaideep Honavar, Angela P Brandon, Judy Creighton, Shannon W Stephens, Charity Morgan, Randal O Dull, Marisa B Marques, Jeffrey D Kerby, Jean-Francois Pittet, Rakesh P Patel |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-03-01
|
Series: | PLoS Medicine |
Online Access: | https://doi.org/10.1371/journal.pmed.1002522 |
Similar Items
-
Correction: Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study.
by: Brant M Wagener, et al.
Published: (2019-11-01) -
Absorbance and redox based approaches for measuring free heme and free hemoglobin in biological matrices
by: Joo-Yeun Oh, et al.
Published: (2016-10-01) -
Preclinical transmission of prions by blood transfusion is influenced by donor genotype and route of infection.
by: M Khalid F Salamat, et al.
Published: (2021-02-01) -
Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections
by: Frank A.D.T.G. Wagener, et al.
Published: (2020-06-01) -
Heme Oxygenase Protects against Placental Vascular Inflammation and Abortion by the Alarmin Heme in Mice
by: Christiaan M. Suttorp, et al.
Published: (2020-07-01)