Harnessing the ECM Microenvironment to Ameliorate Mesenchymal Stromal Cell-Based Therapy in Chronic Lung Diseases

It is known that the cell environment such as biomechanical properties and extracellular matrix (ECM) composition dictate cell behaviour including migration, proliferation, and differentiation. Important constituents of the microenvironment, including ECM molecules such as proteoglycans and glycosam...

Full description

Bibliographic Details
Main Authors: Linda Elowsson Rendin, Anna Löfdahl, Måns Kadefors, Zackarias Söderlund, Emil Tykesson, Sara Rolandsson Enes, Jenny Wigén, Gunilla Westergren-Thorsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
MSC
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.645558/full