Haemolysis and haem oxygenase-1 induction during persistent “asymptomatic” malaria infection in Burkinabé children

Haemolysis and haem oxygenase-1 induction during persistent “asymptomatic” malaria infection in Burkinabé children

Abstract Background The haemolysis associated with clinical episodes of malaria results in the liberation of haem, which activates the enzyme haem oxygenase-1 (HO-1). HO-1 has been shown to reduce neutrophil function and increase susceptibility to invasive bacterial disease. However, the majority of...

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Bibliographic Details
Main Authors: Jason P. Mooney, Aissata Barry, Bronner P. Gonçalves, Alfred B. Tiono, Shehu S. Awandu, Lynn Grignard, Chris J. Drakeley, Christian Bottomley, Teun Bousema, Eleanor M. Riley
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Malaria Journal
Subjects:
Subclinical malaria
Anaemia
Haemolysis
IL-10
HO-1
Burkina Faso
Online Access:http://link.springer.com/article/10.1186/s12936-018-2402-6

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http://link.springer.com/article/10.1186/s12936-018-2402-6

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