The OmpL37 surface-exposed protein is expressed by pathogenic Leptospira during infection and binds skin and vascular elastin.

Pathogenic Leptospira spp. shed in the urine of reservoir hosts into freshwater can be transmitted to a susceptible host through skin abrasions or mucous membranes causing leptospirosis. The infection process involves the ability of leptospires to adhere to cell surface and extracellular matrix comp...

Full description

Bibliographic Details
Main Authors: Marija Pinne, Henry A Choy, David A Haake
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2935396?pdf=render