Vitamin D treatment of peripheral blood mononuclear cells modulated immune activation and reduced susceptibility to HIV-1 infection of CD4+ T lymphocytes.

<h4>Introduction</h4>Mucosal immune activation, in the context of sexual transmission of HIV-1 infection, is crucial, as the increased presence of activated T cells enhance susceptibility to infection. In this regard, it has been proposed that immunomodulatory compounds capable of modula...

Full description

Bibliographic Details
Main Authors: Sandra M Gonzalez, Wbeimar Aguilar-Jimenez, Edison Trujillo-Gil, Wildeman Zapata, Ruey-Chyi Su, T Blake Ball, Maria T Rugeles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222878