Bacterial Genotoxins: Merging the DNA Damage Response into Infection Biology

Bacterial genotoxins are unique among bacterial toxins as their molecular target is DNA. The consequence of intoxication or infection is induction of DNA breaks that, if not properly repaired, results in irreversible cell cycle arrest (senescence) or death of the target cells. At present, only thre...

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Bibliographic Details
Main Authors: Francesca Grasso, Teresa Frisan
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/5/3/1762