Detection and analysis of CpG sites with multimodal DNA methylation level distributions and their relationships with SNPs

Abstract DNA methylation levels at cytosine-phosphate-guanine (CpG) sites with multimodal distributions among different samples have been reported recently. One possible explanation for such variability is that genetic variants might affect epigenetic variation. One obvious case is that mutations su...

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Bibliographic Details
Main Authors: Ke Hu, Jing Li
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Proceedings
Online Access:http://link.springer.com/article/10.1186/s12919-018-0141-x