Targeting extracellular vesicles to injured tissue using membrane cloaking and surface display

Abstract Background Extracellular vesicles (EVs) and exosomes are nano-sized, membrane-bound vesicles shed by most eukaryotic cells studied to date. EVs play key signaling roles in cellular development, cancer metastasis, immune modulation and tissue regeneration. Attempts to modify exosomes to incr...

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Bibliographic Details
Main Authors: Travis J. Antes, Ryan C. Middleton, Kristin M. Luther, Takeshi Ijichi, Kiel A. Peck, Weixin Jane Liu, Jackie Valle, Antonio K. Echavez, Eduardo Marbán
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Nanobiotechnology
Subjects:
EV
Online Access:http://link.springer.com/article/10.1186/s12951-018-0388-4