Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer
Abstract Background The conversion from estrogen-dependent to estrogen-independent state of ER+ breast cancer cells is the key step to promote resistance to endocrine therapies. Although the crucial role of MAPK/ERK signaling pathway in estrogen-independent breast cancer cell growth is well establis...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-10-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-017-0727-3 |