Proteomic modeling for HIV-1 infected microglia-astrocyte crosstalk.
HIV-1-infected and immune competent brain mononuclear phagocytes (MP; macrophages and microglia) secrete cellular and viral toxins that affect neuronal damage during advanced disease. In contrast, astrocytes can affect disease by modulating the nervous system's microenvironment. Interestingly,...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-06-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2429966?pdf=render |