Proteomic modeling for HIV-1 infected microglia-astrocyte crosstalk.

HIV-1-infected and immune competent brain mononuclear phagocytes (MP; macrophages and microglia) secrete cellular and viral toxins that affect neuronal damage during advanced disease. In contrast, astrocytes can affect disease by modulating the nervous system's microenvironment. Interestingly,...

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Bibliographic Details
Main Authors: Tong Wang, Nan Gong, Jianuo Liu, Irena Kadiu, Stephanie D Kraft-Terry, R Lee Mosley, David J Volsky, Pawel Ciborowski, Howard E Gendelman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2429966?pdf=render