D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling

D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling

Background: Emphysematous COPD is characterized by aberrant alveolar repair. Macrophage migration inhibitory factor (MIF) contributes to alveolar repair, but for its structural and functional homolog D-dopachrome tautomerase (DDT) this is unknown. MIF mediates its effects through CD74 and/or C-X-C c...

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Bibliographic Details
Main Authors: Shanshan Song, Bin Liu, Habibie Habibie, Jelle van den Bor, Martine J. Smit, Reinoud Gosens, Xinhui Wu, Corry-Anke Brandsma, Robbert H. Cool, Hidde J. Haisma, Gerrit J. Poelarends, Barbro N. Melgert
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:EBioMedicine
Subjects:
MIF
emphysema
alveolar epithelial cells
type II cells
COPD
CXCR7
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642100205X

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http://www.sciencedirect.com/science/article/pii/S235239642100205X

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