The effects of DPP-4 inhibitor on hypoxia-induced apoptosis in human umbilical vein endothelial cells

The effects of DPP-4 inhibitor on hypoxia-induced apoptosis in human umbilical vein endothelial cells

Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of oral hypoglycemic agents for patients with type 2 diabetes mellitus and have potential antiatherosclerotic properties. Meanwhile, it is unclear how DPP-4 inhibitors have protective effects on atherosclerosis. Our aim was to determine the e...

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Bibliographic Details
Main Authors: Akari Nagamine, Hiroshi Hasegawa, Naoko Hashimoto, Tomoko Yamada-Inagawa, Masanori Hirose, Yuka Kobara, Hiroyuki Tadokoro, Yoshio Kobayashi, Hiroyuki Takano
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Journal of Pharmacological Sciences
Subjects:
Endothelial cell
Dipeptidyl peptidase-4
Apoptosis
Hypoxia
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316301724

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http://www.sciencedirect.com/science/article/pii/S1347861316301724

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