Evaluation of HER2 and p53 expression in predicting response to docetaxel-based first-line chemotherapy in advanced breast cancer

<p>Abstract</p> <p>Background</p> <p>The human epidermal growth factor receptor 2 (HER2) and p53 pathways may be involved in chemotherapy sensitivity and/or resistance. We explore the value of HER2 and p53 status to foretell docetaxel sensitivity in advanced breast canc...

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Bibliographic Details
Main Authors: Martini Leonardo, De Luca Filomena, Valsuani Chiara, Tartarelli Gianna, Puccetti Cheti, Siclari Olimpia, Viacava Paolo, Donati Sara, Camerini Andrea, Cavazzana Andrea, Amoroso Domenico
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/38