Multimorbidity among Two Million Adults in China
To explore the multimorbidity prevalence and patterns among middle-aged and older adults from China. Data on thirteen chronic diseases were collected from 2,097,150 participants aged over 45 years between January 1st 2011 and December 31st 2015 from Beijing Medical Claim Data for Employees. Associat...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
|
Series: | International Journal of Environmental Research and Public Health |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-4601/17/10/3395 |
id |
doaj-a7f8b90750c04f89ad2573fff1703184 |
---|---|
record_format |
Article |
spelling |
doaj-a7f8b90750c04f89ad2573fff17031842020-11-25T02:31:32ZengMDPI AGInternational Journal of Environmental Research and Public Health1661-78271660-46012020-05-01173395339510.3390/ijerph17103395Multimorbidity among Two Million Adults in ChinaXiaowen Wang0Shanshan Yao1Mengying Wang2Guiying Cao3Zishuo Chen4Ziting Huang5Yao Wu6Ling Han7Beibei Xu8Yonghua Hu9Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, ChinaDepartment of Medicine, Yale School of Medicine, New Haven, CT 06510, USAMedical Informatics Center, Peking University Health Science Center, Beijing 100191, ChinaDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, ChinaTo explore the multimorbidity prevalence and patterns among middle-aged and older adults from China. Data on thirteen chronic diseases were collected from 2,097,150 participants aged over 45 years between January 1st 2011 and December 31st 2015 from Beijing Medical Claim Data for Employees. Association rule mining and hierarchical cluster analysis were applied to assess multimorbidity patterns. Multimorbidity prevalence was 51.6% and 81.3% in the middle-aged and older groups, respectively. The most prevalent disease pair was that of osteoarthritis and rheumatoid arthritis (OARA) with hypertension (HT) (middle-aged: 22.5%; older: 41.8%). Ischaemic heart disease (IHD), HT, and OARA constituted the most common triad combination (middle-aged: 11.0%; older: 31.2%). Among the middle-aged group, the strongest associations were found in a combination of cerebrovascular disease (CBD), OARA, and HT with IHD in males (lift = 3.49), and CBD, OARA, and COPD with IHD in females (lift = 3.24). Among older patients, glaucoma and cataracts in females (lift = 2.95), and IHD, OARA, and glaucoma combined with cataracts in males (lift = 2.45) were observed. Visual impairment clusters, a mixed cluster of OARA, IHD, COPD, and cardiometabolic clusters were detected. Multimorbidity is prevalent among middle-aged and older Chinese individuals. The observations of multimorbidity patterns have implications for improving preventive care and developing appropriate guidelines for morbidity treatment.https://www.mdpi.com/1660-4601/17/10/3395multimorbidityprevalencepatternchronic diseasesChina |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xiaowen Wang Shanshan Yao Mengying Wang Guiying Cao Zishuo Chen Ziting Huang Yao Wu Ling Han Beibei Xu Yonghua Hu |
spellingShingle |
Xiaowen Wang Shanshan Yao Mengying Wang Guiying Cao Zishuo Chen Ziting Huang Yao Wu Ling Han Beibei Xu Yonghua Hu Multimorbidity among Two Million Adults in China International Journal of Environmental Research and Public Health multimorbidity prevalence pattern chronic diseases China |
author_facet |
Xiaowen Wang Shanshan Yao Mengying Wang Guiying Cao Zishuo Chen Ziting Huang Yao Wu Ling Han Beibei Xu Yonghua Hu |
author_sort |
Xiaowen Wang |
title |
Multimorbidity among Two Million Adults in China |
title_short |
Multimorbidity among Two Million Adults in China |
title_full |
Multimorbidity among Two Million Adults in China |
title_fullStr |
Multimorbidity among Two Million Adults in China |
title_full_unstemmed |
Multimorbidity among Two Million Adults in China |
title_sort |
multimorbidity among two million adults in china |
publisher |
MDPI AG |
series |
International Journal of Environmental Research and Public Health |
issn |
1661-7827 1660-4601 |
publishDate |
2020-05-01 |
description |
To explore the multimorbidity prevalence and patterns among middle-aged and older adults from China. Data on thirteen chronic diseases were collected from 2,097,150 participants aged over 45 years between January 1st 2011 and December 31st 2015 from Beijing Medical Claim Data for Employees. Association rule mining and hierarchical cluster analysis were applied to assess multimorbidity patterns. Multimorbidity prevalence was 51.6% and 81.3% in the middle-aged and older groups, respectively. The most prevalent disease pair was that of osteoarthritis and rheumatoid arthritis (OARA) with hypertension (HT) (middle-aged: 22.5%; older: 41.8%). Ischaemic heart disease (IHD), HT, and OARA constituted the most common triad combination (middle-aged: 11.0%; older: 31.2%). Among the middle-aged group, the strongest associations were found in a combination of cerebrovascular disease (CBD), OARA, and HT with IHD in males (lift = 3.49), and CBD, OARA, and COPD with IHD in females (lift = 3.24). Among older patients, glaucoma and cataracts in females (lift = 2.95), and IHD, OARA, and glaucoma combined with cataracts in males (lift = 2.45) were observed. Visual impairment clusters, a mixed cluster of OARA, IHD, COPD, and cardiometabolic clusters were detected. Multimorbidity is prevalent among middle-aged and older Chinese individuals. The observations of multimorbidity patterns have implications for improving preventive care and developing appropriate guidelines for morbidity treatment. |
topic |
multimorbidity prevalence pattern chronic diseases China |
url |
https://www.mdpi.com/1660-4601/17/10/3395 |
work_keys_str_mv |
AT xiaowenwang multimorbidityamongtwomillionadultsinchina AT shanshanyao multimorbidityamongtwomillionadultsinchina AT mengyingwang multimorbidityamongtwomillionadultsinchina AT guiyingcao multimorbidityamongtwomillionadultsinchina AT zishuochen multimorbidityamongtwomillionadultsinchina AT zitinghuang multimorbidityamongtwomillionadultsinchina AT yaowu multimorbidityamongtwomillionadultsinchina AT linghan multimorbidityamongtwomillionadultsinchina AT beibeixu multimorbidityamongtwomillionadultsinchina AT yonghuahu multimorbidityamongtwomillionadultsinchina |
_version_ |
1724823967347245056 |