Choosing an imbalance metric for covariate-constrained randomization in multiple-arm cluster-randomized trials

Choosing an imbalance metric for covariate-constrained randomization in multiple-arm cluster-randomized trials

Abstract Background In cluster-randomized controlled trials (C-RCTs), covariate-constrained randomization (CCR) methods efficiently control imbalance in multiple baseline cluster-level variables, but the choice of imbalance metric to define the subset of “adequately balanced” possible allocation sch...

Full description

Bibliographic Details
Main Authors: Jody D. Ciolino, Alicia Diebold, Jessica K. Jensen, Gerald W. Rouleau, Kimberly K. Koloms, Darius Tandon
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Trials
Subjects:
Cluster randomization
Covariate-constrained randomization
Cluster-randomized controlled trial
Continuous covariate
Imbalance
Online Access:http://link.springer.com/article/10.1186/s13063-019-3324-5

Internet

http://link.springer.com/article/10.1186/s13063-019-3324-5

Similar Items