Aminoquinolines afford resistance to cerebral malaria in susceptible mice

Objectives: Malaria treatment is impeded by increasing resistance to conventional antimalarial drugs. Here we explored the activity of ten novel benzothiophene, thiophene and benzene aminoquinolines. Methods: In vitro testing was performed by the lactate dehydrogenase assay in chloroquine (CQ)-sensi...

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Main Authors: Jelena Srbljanović, Branko Bobić, Tijana Štajner, Aleksandra Uzelac, Igor Opsenica, Nataša Terzić-Jovanović, Neda Bauman, Bogdan A. Šolaja, Olgica Djurković-Djaković
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716520302022