The role of TGF-β-related signal transduction pathways in pathogenesis of epithelial-mesenchymal transition as a key element in cancer development and progression

The role of TGF-β-related signal transduction pathways in pathogenesis of epithelial-mesenchymal transition as a key element in cancer development and progression

Epithelial-mesenchymal transition (EMT) is a biological process that drives polarized, immotile epithelial cells to undergo multiple biochemical changes to acquire a mesenchymal cell phenotype. The characteristic features of EMT are cell apolarity, loss of cellular adhesion, reduced expression of E-...

Full description

Bibliographic Details
Main Authors: Małgorzata Pieniążek, Piotr Donizy, Marcin Ziętek, Bartłomiej Szynglarewicz, Rafał Matkowski
Format: Article
Language:English
Published: Index Copernicus International S.A. 2012-09-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
Epithelial-mesenchymal transition
TGF-β
E-cadherin
carcinogenesis
przejście nabłonkowo-mezenchymalne
E-kadheryna
karcynogeneza
Online Access:http://journals.indexcopernicus.com/fulltxt.php?ICID=1009653

Internet

http://journals.indexcopernicus.com/fulltxt.php?ICID=1009653

Similar Items