Evaluation of a rat meibomian gland dysfunction model induced by closure of meibomian gland orifices

Evaluation of a rat meibomian gland dysfunction model induced by closure of meibomian gland orifices

AIM: To find a stable, inexpensive, and reliable method to produce a rat meibomian gland dysfunction (MGD) model. METHODS: We inserted slim guidewires into the meibomian gland orifices of twelve Brown Norway rats and fulgurized every guidewire to destroy part of the meibomian gland. We then observe...

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Bibliographic Details
Main Authors: Zi-Yi Dong, Ming Ying, Jie Zheng, Lan-Jun Hu, Jiang-Yan Xie, Yi Ma
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-07-01
Series:International Journal of Ophthalmology
Subjects:
1083
meibomian gland dysfunction
animal model
epithelial growth factor
interleukin-6
interleukin-8
tumor necrosis factor-α
Ki67
Online Access:http://www.ijo.cn/en_publish/2018/7/20180701.pdf

Internet

http://www.ijo.cn/en_publish/2018/7/20180701.pdf

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