Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus Infection

Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus Infection

Background: Bile acids (BAs) are steroid molecules that are synthesized in the liver. In addition to their important role as a surfactant in solubilizing lipids and promoting the absorption of lipids in the gastrointestinal tract, they act as inflammagens. The role of BAs and their receptor farnesoi...

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Bibliographic Details
Main Authors: Nadine Honke, Namir Shaabani, Cornelia Hardt, Caroline Krings, Dieter Häussinger, Philipp A. Lang, Karl S.  Lang, Verena Keitel
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Monocytes
LCMV
NR1H4
FXR
IFN-I
Bile acids
Online Access:http://www.karger.com/Article/FullText/456168

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http://www.karger.com/Article/FullText/456168

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