Radiating amyloid fibril formation on the surface of lipid membranes through unit-assembly of oligomeric species of α-synuclein.

Radiating amyloid fibril formation on the surface of lipid membranes through unit-assembly of oligomeric species of α-synuclein.

BACKGROUND: Lewy body in the substantia nigra is a cardinal pathological feature of Parkinson's disease. Despite enormous efforts, the cause-and-effect relationship between Lewy body formation and the disorder is yet to be explicitly unveiled. METHODOLOGY/PRINCIPAL FINDINGS: Here, we showed tha...

Full description

Bibliographic Details
Main Authors: Jung-Ho Lee, Chul-Suk Hong, Soonkoo Lee, Jee-Eun Yang, Yong Il Park, Daekyun Lee, Taeghwan Hyeon, Seunho Jung, Seung R Paik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471876?pdf=render

Internet

http://europepmc.org/articles/PMC3471876?pdf=render

Similar Items