The Pharmacological NF-κB Inhibitor BAY11-7082 Induces Cell Apoptosis and Inhibits the Migration of Human Uveal Melanoma Cells

The Pharmacological NF-κB Inhibitor BAY11-7082 Induces Cell Apoptosis and Inhibits the Migration of Human Uveal Melanoma Cells

Uveal melanomas are highly metastatic and have high rate of recurrence due to the lack of effective systemic therapy. The identification of important survival pathways in uveal melanomas provides novel therapeutic targets for effective treatment. In the present study, we found that the NF-&#...

Full description

Bibliographic Details
Main Authors: Xianqun Fan, Fuxiang Chen, Shengfang Ge, Dan Hu, Biyun Cun, Qingqiong Luo, Shuiqing Hu
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:International Journal of Molecular Sciences
Subjects:
uveal melanoma
NF-&#954
B
BAY11-7082
apoptosis
cell migration
Online Access:http://www.mdpi.com/1422-0067/13/12/15653

Internet

http://www.mdpi.com/1422-0067/13/12/15653

Similar Items