Untargeted Metabolic Profiling Cell-Based Approach of Pulmonary Artery Smooth Muscle Cells in Response to High Glucose and the Effect of the Antioxidant Vitamins D and E

Untargeted Metabolic Profiling Cell-Based Approach of Pulmonary Artery Smooth Muscle Cells in Response to High Glucose and the Effect of the Antioxidant Vitamins D and E

Pulmonary arterial hypertension (PAH) is a multi-factorial disease characterized by the hyperproliferation of pulmonary artery smooth muscle cells (PASMCs). Excessive reactive oxygen species (ROS) formation resulted in alterations of the structure and function of pulmonary arterial walls, leading to...

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Bibliographic Details
Main Authors: Abdulwahab Alamri, Abdulhadi S. Burzangi, Paul Coats, David G. Watson
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Metabolites
Subjects:
oxidative stress
pulmonary arterial hypertension
smooth muscle cells
metabolomics
metabolic profiling
diabetes mellitus
hyperglycaemia
vitamin D
vitamin E
Online Access:https://www.mdpi.com/2218-1989/8/4/87

Internet

https://www.mdpi.com/2218-1989/8/4/87

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