Voltage-Dependent Sarcolemmal Ion Channel Abnormalities in the Dystrophin-Deficient Heart

Voltage-Dependent Sarcolemmal Ion Channel Abnormalities in the Dystrophin-Deficient Heart

Mutations in the gene encoding for the intracellular protein dystrophin cause severe forms of muscular dystrophy. These so-called dystrophinopathies are characterized by skeletal muscle weakness and degeneration. Dystrophin deficiency also gives rise to considerable complications in the heart, inclu...

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Bibliographic Details
Main Authors: Xaver Koenig, Janine Ebner, Karlheinz Hilber
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
animal models
calcium channels
cardiac ion channel abnormalities
dystrophic cardiomyopathy
dystrophin deficiency
dystrophinopathies
potassium channels
sodium channels
Online Access:https://www.mdpi.com/1422-0067/19/11/3296

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https://www.mdpi.com/1422-0067/19/11/3296

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