MaGIC: a machine learning tool set and web application for monoallelic gene inference from chromatin

MaGIC: a machine learning tool set and web application for monoallelic gene inference from chromatin

Abstract Background A large fraction of human and mouse autosomal genes are subject to random monoallelic expression (MAE), an epigenetic mechanism characterized by allele-specific gene expression that varies between clonal cell lineages. MAE is highly cell-type specific and mapping it in a large nu...

Full description

Bibliographic Details
Main Authors: Svetlana Vinogradova, Sachit D. Saksena, Henry N. Ward, Sébastien Vigneau, Alexander A. Gimelbrant
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Bioinformatics
Subjects:
Monoallelic expression
Chromatin
Chromatin signature
Software pipeline
Shiny app
Online Access:http://link.springer.com/article/10.1186/s12859-019-2679-7

Internet

http://link.springer.com/article/10.1186/s12859-019-2679-7

Similar Items