Natural Killer Cell Function Tests by Flowcytometry-Based Cytotoxicity and IFN-γ Production for the Diagnosis of Adult Hemophagocytic Lymphohistiocytosis

Natural Killer Cell Function Tests by Flowcytometry-Based Cytotoxicity and IFN-γ Production for the Diagnosis of Adult Hemophagocytic Lymphohistiocytosis

Although natural killer (NK) cell function is a hallmark of hemophagocytic lymphohistiocytosis (HLH), there is no standard method or data on its diagnostic value in adults. Thus, we performed a single-center retrospective study of 119 adult patients with suspected HLH. NK cell function was determine...

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Bibliographic Details
Main Authors: Hyeyoung Lee, Hoon Seok Kim, Jong-Mi Lee, Ki Hyun Park, Ae-Ran Choi, Jae-Ho Yoon, Hyejin Ryu, Eun-Jee Oh
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
hemophagocytic lymphohistiocytosis
natural killer cell activity
interferon-gamma
cytotoxicity
cytokine
nk cell subset
Online Access:https://www.mdpi.com/1422-0067/20/21/5413

Internet

https://www.mdpi.com/1422-0067/20/21/5413

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