Utility of LC-MS Surrogate Peptide Methodology in the Development of a Combinectin, a Unique Anti-HIV Biologic Drug
OBJECTIVES: The anti-HIV biologic drug combinectin is a construct of three independent HIV entry inhibitors and a pharmacokinetic (PK) enhancer, which together exhibit a synergistic increase of potency compared to the individual components. Consequently, the integrity of the macromolecule over time...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Betasciencepress Publishers
2021-07-01
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| Series: | Journal of Applied Bioanalysis |
| Subjects: | |
| Online Access: | https://doi.org/10.17145/jab.21.007 |