Effects of mavoglurant on visual attention and pupil reactivity while viewing photographs of faces in Fragile X Syndrome.

<h4>Background</h4>Numerous preclinical studies have supported the theory that enhanced activation of mGluR5 signaling, due to the absence or reduction of the FMR1 protein, contributes to cognitive and behavioral deficits in patients with fragile X syndrome (FXS). However multiple phase...

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Bibliographic Details
Main Authors: David Hessl, Danielle Harvey, Stephanie Sansone, Crystal Crestodina, Jamie Chin, Reshma Joshi, Randi J Hagerman, Elizabeth Berry-Kravis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209984