Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles

Targeting the adenosinergic pathway represents a therapeutic option to overcome tumor-induced immunosuppression. Here the authors design E-selectin-modified thermal-sensitive micelles loaded with doxorubicin and an adenosine A2 receptor antagonist to enhance chemotherapy-induced anti-tumor immune re...

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Bibliographic Details
Main Authors: Jing Qi, Feiyang Jin, Yuchan You, Yan Du, Di Liu, Xiaoling Xu, Jun Wang, Luwen Zhu, Minjiang Chen, Gaofeng Shu, Liming Wu, Jiansong Ji, Yongzhong Du
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24902-2