Computational Characterizations of the Interactions Between the Pontacyl Violet 6R and Exoribonuclease as a Potential Drug Target Against SARS-CoV-2

Computational Characterizations of the Interactions Between the Pontacyl Violet 6R and Exoribonuclease as a Potential Drug Target Against SARS-CoV-2

We report a molecular-docking and virtual-screening-based identification and characterization of interactions of lead molecules with exoribonuclease (ExoN) enzyme in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). From previously identified DEDDh/DEEDh subfamily nuclease inhibitors, ou...

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Bibliographic Details
Main Authors: Rangika Munaweera, Ying S. Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Chemistry
Subjects:
exoribonuclease
SARS-CoV-2
pontacyl violet 6R
DEDDh exonucleases
RNA-dependent RNA polymerase
orthocoronavirinae
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2020.627340/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2020.627340/full

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