The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation.

Epstein-Barr virus (EBV) is a human herpesvirus that persists as a largely subclinical infection in the vast majority of adults worldwide. Recent evidence indicates that an important component of the persistence strategy involves active interference with the MHC class I antigen processing pathway du...

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Bibliographic Details
Main Authors: Jianmin Zuo, Andrew Currin, Bryan D Griffin, Claire Shannon-Lowe, Wendy A Thomas, Maaike E Ressing, Emmanuel J H J Wiertz, Martin Rowe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2603334?pdf=render