Interferon-γ responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission

Background Malaria elimination campaigns are planned or active in many countries. The effects of malaria elimination on immune responses such as antigen-specific IFN- γ responses are not well characterized. Methods IFN- γ responses to the P. falciparum antigens circumsporozoite protein, liver stage...

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Bibliographic Details
Main Authors: Cyrus Ayieko, Bilha S. Ogola, Lyticia Ochola, Gideon A.M. Ngwena, George Ayodo, James S. Hodges, Gregory S. Noland, Chandy C. John
Format: Article
Language:English
Published: PeerJ Inc. 2017-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2855.pdf