ANTIDIURETIC EFFECTS OF THE ENDOTHELIN RECEPTOR ANTAGONIST AVOSENTAN

ANTIDIURETIC EFFECTS OF THE ENDOTHELIN RECEPTOR ANTAGONIST AVOSENTAN

Several clinical studies have investigated the potential benefits of endothelin receptor antagonism in chronic pathologies such as diabetic kidney disease. However, fluid retention and edema have been identified as major side effects of endothelin receptor antagonists. In the present study we hypoth...

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Bibliographic Details
Main Authors: Ovidiu Constantin Baltatu, Radu eIliescu, Christian eZaugg, Jane F. Reckelhoff, Pat eLouie, Christoph eSchumacher, Luciana Aparecida Campos
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Physiology
Subjects:
Diuresis
Renal
endothelin receptor antagonist
fluid retention
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00103/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00103/full

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