Pre-treatment With Ranibizumab Aggravates PDT Injury and Alleviates Inflammatory Response in Choroid-Retinal Endothelial Cells

Pre-treatment With Ranibizumab Aggravates PDT Injury and Alleviates Inflammatory Response in Choroid-Retinal Endothelial Cells

Polypoidal choroidal vasculopathy (PCV) is the predominant subtype of exudative age-related macular degeneration in Asians. Although photodynamic therapy (PDT) is widely used for PCV treatment, its long-term beneficial effects are unsatisfactory. Accumulating clinical investigations suggest that com...

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Bibliographic Details
Main Authors: Yang Liu, Min Zhu, Ruowen Gong, Xin Wang, Lei Li, Gezhi Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
PDT
anti-VEGF
pre-treatment
necroptosis
NLRP3/IL-1β inflammatory response
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00608/full

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