The anti-metastatic nm23-1 gene is needed for the final step of mammary duct maturation of the mouse nipple.

Nm23/NDP kinases are multifunctional enzymes involved in the general homeostasis of triphosphate nucleosides. Numerous studies have shown that NDPKs also serve as regulatory factors of various cell activities, not always connected to nucleotide phosphorylation. In particular, the nme-1 gene, encodin...

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Bibliographic Details
Main Authors: Camille Deplagne, Evelyne Peuchant, Isabelle Moranvillier, Pierre Dubus, Sandrine Dabernat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3072419?pdf=render