AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice

AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice

Masato Iwabu and Miki Okada-Iwabu et al. investigate whether diabetic phenotypes associated with disruption of the adiponectin receptor (AdipoR1) can be reversed in diabetic mice by upregulation of the receptor. They show that overexpressing human AdipoR1 in the muscles of diabetic mice increased in...

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Bibliographic Details
Main Authors: Masato Iwabu, Miki Okada-Iwabu, Hiroaki Tanabe, Nozomi Ohuchi, Keiko Miyata, Toshiko Kobori, Sara Odawara, Yuri Kadowaki, Shigeyuki Yokoyama, Toshimasa Yamauchi, Takashi Kadowaki
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01579-9

Internet

https://doi.org/10.1038/s42003-020-01579-9

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