Molecular features of tumor-derived genetic alterations in circulating cell-free DNA in virtue of autopsy analysis

Molecular features of tumor-derived genetic alterations in circulating cell-free DNA in virtue of autopsy analysis

Abstract In cancer patients, circulating cell-free DNA (cfDNA) includes tumor-derived DNA (tDNA). cfDNA has been used clinically for non-invasive gene mutation testing. The aim of this study was to characterize the features of the genetic alterations detected in cfDNA. This study included 6 patients...

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Bibliographic Details
Main Authors: Hayato Koba, Hideharu Kimura, Taro Yoneda, Takashi Sone, Noriyuki Ohkura, Johsuke Hara, Kazuyoshi Hosomichi, Atsushi Tajima, Kazuo Kasahara
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87094-1

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