Molecular modeling, synthesis, characterization and pharmacological evaluation of benzo[d]oxazole derivatives as non-steroidal anti-inflammatory agents
A series of N-(2-(4-chlorobenzyl)benzo[d]oxazol-5-yl)-3-substituted-propanamide (3a–3n) were synthesized and evaluated for their acute and chronic anti-inflammatory potential. The structure of the compounds was elucidated by elemental and spectral (IR, 1H NMR and MS) analysis. The synthesized compou...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
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Series: | Saudi Pharmaceutical Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S131901641500081X |