Integrated systems analysis of salivary gland transcriptomics reveals key molecular networks in Sjögren’s syndrome

Integrated systems analysis of salivary gland transcriptomics reveals key molecular networks in Sjögren’s syndrome

Abstract Background Treatment of patients with Sjögren’s syndrome (SjS) is a clinical challenge with high unmet needs. Gene expression profiling and integrative network-based approaches to complex disease can offer an insight on molecular characteristics in the context of clinical setting. Methods A...

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Bibliographic Details
Main Authors: Hong Ki Min, Su-Jin Moon, Kyung-Su Park, Ki-Jo Kim
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Arthritis Research & Therapy
Subjects:
Sjögren’s syndrome
Salivary gland
Gene expression profiles
Unsupervised clustering
Key driver analysis
Online Access:https://doi.org/10.1186/s13075-019-2082-9

Internet

https://doi.org/10.1186/s13075-019-2082-9

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