17β-Estradiol Attenuates Intracerebral Hemorrhage-Induced Blood–Brain Barrier Injury and Oxidative Stress Through SRC3-Mediated PI3K/Akt Signaling Pathway in a Mouse Model
Estrogen is neuroprotective in brain injury models, and steroid receptor cofactor 3 (SRC3) mediates estrogen signaling. We aimed to investigate whether and how SRC3 is involved in the neuroprotective effects of 17ß-estradiol (E2) in a mouse model of intracerebral hemorrhage (ICH). Ovariectomized fem...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-09-01
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Series: | ASN Neuro |
Online Access: | https://doi.org/10.1177/17590914211038443 |