Increased insulin-like growth factor 1 production by polyploid adipose stem cells promotes growth of breast cancer cells

Increased insulin-like growth factor 1 production by polyploid adipose stem cells promotes growth of breast cancer cells

Abstract Background Adipose-tissue stem cells (ASCs) are subject of intensive research since their successful use in regenerative therapy. The drawback of ASCs is that they may serve as stroma for cancer cells and assist tumor progression. It is disquieting that ASCs frequently undergo genetic and e...

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Bibliographic Details
Main Authors: Roberta Fajka-Boja, Annamária Marton, Anna Tóth, Péter Blazsó, Vilmos Tubak, Balázs Bálint, István Nagy, Zoltán Hegedűs, Csaba Vizler, Robert L. Katona
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Cancer
Subjects:
Adipose stem cells
Breast cancer
Insulin-like growth factor 1
Polyploidy
Transcriptome
Online Access:http://link.springer.com/article/10.1186/s12885-018-4781-z

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http://link.springer.com/article/10.1186/s12885-018-4781-z

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